Journal of Breath Research

期刊简介：Journal of Breath Research is dedicated to all aspects of scientific breath research. The traditional focus is on analysis of volatile compounds and aerosols in exhaled breath for the investigation of exogenous exposures, metabolism, toxicology, health status and the diagnosis of disease and breath odours. The journal also welcomes other breath-related topics.Typical areas of interest include:Big laboratory instrumentation: describing new state-of-the-art analytical instrumentation capable of performing high-resolution discovery and targeted breath research; exploiting complex technologies drawn from other areas of biochemistry and genetics for breath research.Engineering solutions: developing new breath sampling technologies for condensate and aerosols, for chemical and optical sensors, for extraction and sample preparation methods, for automation and standardization, and for multiplex analyses to preserve the breath matrix and facilitating analytical throughput. Measure exhaled constituents (e.g. CO2, acetone, isoprene) as markers of human presence or mitigate such contaminants in enclosed environments.Human and animal in vivo studies: decoding the 'breath exposome', implementing exposure and intervention studies, performing cross-sectional and case-control research, assaying immune and inflammatory response, and testing mammalian host response to infections and exogenous exposures to develop information directly applicable to systems biology. Studying inhalation toxicology; inhaled breath as a source of internal dose; resultant blood, breath and urinary biomarkers linked to inhalation pathway.Cellular and molecular level in vitro studies.Clinical, pharmacological and forensic applications.Mathematical, statistical and graphical data interpretation.

【译文】《呼吸研究杂志》致力于所有科学呼吸研究的各个方面。传统上，其重点是分析呼出气体中的挥发性化合物和气溶胶，以研究外源性暴露、代谢、毒理学、健康状况以及疾病和呼吸气味的诊断。该杂志还欢迎其他与呼吸相关的话题。典型的兴趣领域包括：大型实验室仪器：描述能够进行高分辨率发现和靶向呼吸研究的新一代分析仪器；利用来自生物化学和遗传学等其他领域的复杂技术进行呼吸研究。工程解决方案：开发新的呼吸采样技术，用于冷凝物和气溶胶、化学和光学传感器、提取和样品制备方法、自动化和标准化，以及多重分析，以保护呼吸基质并促进分析通量。测量呼出成分（例如，二氧化碳、丙酮、异戊二烯）作为人类存在或封闭环境中此类污染物的指标。人体和动物体内研究：解码‘呼吸暴露组’，实施暴露和干预研究，进行横断面和病例对照研究，检测免疫和炎症反应，以及测试哺乳动物宿主对感染和外源性暴露的反应，以开发直接应用于系统生物学的信息。研究吸入毒理学；吸入呼吸作为内部剂量来源；与吸入途径相关的血液、呼吸和尿液生物标志物。细胞和分子水平的体外研究。临床、药理和法医应用。数学、统计和图形数据分析。