SLAS DISCOVERY

期刊简介：Advancing Life Sciences R&D: SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease.SLAS Discovery is a peer-reviewed journal that publishes scientific reports that enable and improve target validation, evaluate current drug discovery technologies, provide novel research tools, and incorporate research approaches that enhance depth of knowledge and drug discovery success.SLAS Discovery emphasizes scientific and technical advances in target identification/validation (including chemical probes, RNA silencing, gene editing technologies); biomarker discovery; assay development; virtual, medium- or high-throughput screening (biochemical and biological, biophysical, phenotypic, toxicological, ADME); lead generation/optimization; chemical biology; and informatics (data analysis, image analysis, statistics, bio- and chemo-informatics). Review articles on target biology, new paradigms in drug discovery and advances in drug discovery technologies.SLAS Discovery is of particular interest to those involved in analytical chemistry, applied microbiology, automation, biochemistry, bioengineering, biomedical optics, biotechnology, bioinformatics, cell biology, DNA science and technology, genetics, information technology, medicinal chemistry, molecular biology, natural products chemistry, organic chemistry, pharmacology, spectroscopy, and toxicology.SLAS Discovery is a member of the Committee on Publication Ethics (COPE) and was published previously (1996-2016) as the Journal of Biomolecular Screening (JBS).

【译文】推进生命科学研发：SLAS Discovery报道科学家如何开发和使用新技术或方法，以提供和表征化学和生物工具，以理解和治疗人类疾病。SLAS Discovery是一本同行评审期刊，发表能够促进和改进靶点验证、评估当前药物发现技术、提供新型研究工具以及结合增强知识深度和药物发现成功的研究方法的科学报告。SLAS Discovery强调靶点识别/验证（包括化学探针、RNA沉默、基因编辑技术）的科学和技术进步；生物标志物发现；检测方法开发；虚拟、中或高通量筛选（生化、生物、生物物理、表型、毒理学、ADME）；先导化合物生成/优化；化学生物学；以及信息学（数据分析、图像分析、统计学、生物和化学信息学）。关于靶点生物学、药物发现新范式和药物发现技术进展的综述文章。SLAS Discovery特别吸引那些从事分析化学、应用微生物学、自动化、生物化学、生物工程、生物医学光学、生物技术、生物信息学、细胞生物学、DNA科学和技术、遗传学、信息技术、药物化学、分子生物学、天然产物化学、有机化学、药理学、光谱学和毒理学的人。SLAS Discovery是出版伦理委员会（COPE）的成员，之前（1996-2016年）作为《生物分子筛选杂志》（JBS）出版。