Chromatographia

期刊简介：Separation sciences, in all their various forms such as chromatography, field-flow fractionation, and electrophoresis, provide some of the most powerful techniques in analytical chemistry and are applied within a number of important application areas, including archaeology, biotechnology, clinical, environmental, food, medical, petroleum, pharmaceutical, polymer and biopolymer research. Beyond serving analytical purposes, separation techniques are also used for preparative and process-scale applications. The scope and power of separation sciences is significantly extended by combination with spectroscopic detection methods (e.g., laser-based approaches, nuclear-magnetic resonance, Raman, chemiluminescence) and particularly, mass spectrometry, to create hyphenated techniques. In addition to exciting new developments in chromatography, such as ultra high-pressure systems, multidimensional separations, and high-temperature approaches, there have also been great advances in hybrid methods combining chromatography and electro-based separations, especially on the micro- and nanoscale. Integrated biological procedures (e.g., enzymatic, immunological, receptor-based assays) can also be part of the overall analytical process.

【译文】分离科学，包括色谱法、场流分离法、电泳等所有各种形式，是分析化学中最强大的技术之一，并在包括考古学、生物技术、临床、环境、食品、医疗、石油、制药、聚合物和生物聚合物研究在内的许多重要应用领域得到应用。除了服务于分析目的外，分离技术也用于制备和工艺规模的应用。通过结合光谱检测方法（例如，基于激光的方法、核磁共振、拉曼、化学发光）和尤其是质谱，分离科学的范围和力量得到了显著扩展，从而创建了联用技术。除了色谱法在超高压系统、多维分离和高温方法等方面令人兴奋的新发展之外，还有结合色谱和基于电的分离的混合方法在微米和纳米尺度上的巨大进步。集成生物程序（例如，酶联、免疫学、受体基检测）也可以是整体分析过程的一部分。