Molecular & Cellular Proteomics

期刊简介：The mission of MCP is to foster the development and applications of proteomics in both basic and translational research. MCP will publish manuscripts that report significant new biological or clinical discoveries underpinned by proteomic observations across all kingdoms of life. Manuscripts must define the biological roles played by the proteins investigated or their mechanisms of action.The journal also emphasizes articles that describe innovative new computational methods and technological advancements that will enable future discoveries. Manuscripts describing such approaches do not have to include a solution to a biological problem, but must demonstrate that the technology works as described, is reproducible and is appropriate to uncover yet unknown protein/proteome function or properties using relevant model systems or publicly available data.Scope:-Fundamental studies in biology, including integrative "omics" studies, that provide mechanistic insights-Novel experimental and computational technologies-Proteogenomic data integration and analysis that enable greater understanding of physiology and disease processes-Pathway and network analyses of signaling that focus on the roles of post-translational modifications-Studies of proteome dynamics and quality controls, and their roles in disease-Studies of evolutionary processes effecting proteome dynamics, quality and regulation-Chemical proteomics, including mechanisms of drug action-Proteomics of the immune system and antigen presentation/recognition-Microbiome proteomics, host-microbe and host-pathogen interactions, and their roles in health and disease-Clinical and translational studies of human diseases-Metabolomics to understand functional connections between genes, proteins and phenotypes

【译文】MCP的使命是促进蛋白质组学在基础和转化研究中的应用和发展。MCP将发表报告蛋白质组学观察支持的所有生命王国的重大新生物或临床发现的论文。必须定义所研究的蛋白质的生物作用或其作用机制。该期刊还强调描述创新的新计算方法和技术进步的文章，这些方法和进步将使未来的发现成为可能。描述此类方法的论文不必包括解决生物学问题的解决方案，但必须证明该技术按描述工作，可重复，并且适用于使用相关模型系统或公开可用的数据揭示尚不为人知的蛋白质/蛋白质组功能或特性。