Molecular Imaging and Biology

期刊简介：Molecular Imaging and Biology (MIB) invites original contributions (research articles, review articles, commentaries, etc.) on the utilization of molecular imaging (i.e., nuclear imaging, optical imaging, autoradiography and pathology, MRI, MPI, ultrasound imaging, radiomics/genomics etc.) to investigate questions related to biology and health. The objective of MIB is to provide a forum to the discovery of molecular mechanisms of disease through the use of imaging techniques. We aim to investigate the biological nature of disease in patients and establish new molecular imaging diagnostic and therapy procedures.Some areas that are covered are:Preclinical and clinical imaging of macromolecular targets (e.g., genes, receptors, enzymes) involved in significant biological processes.The design, characterization, and study of new molecular imaging probes and contrast agents for the functional interrogation of macromolecular targets.Development and evaluation of imaging systems including instrumentation, image reconstruction algorithms, image analysis, and display.Development of molecular assay approaches leading to quantification of the biological information obtained in molecular imaging.Study of in vivo animal models of disease for the development of new molecular diagnostics and therapeutics.Extension of in vitro and in vivo discoveries using disease models, into well designed clinical research investigations.Clinical molecular imaging involving clinical investigations, clinical trials and medical management or cost-effectiveness studies.

【译文】分子成像与生物学（MIB）邀请原创贡献（研究文章、综述文章、评论等），探讨分子成像（即核成像、光学成像、自显影和病理学、MRI、MPI、超声成像、放射组学/基因组学等）在生物学和健康相关问题研究中的应用。MIB的目标是通过成像技术发现疾病的分子机制。我们旨在研究患者的疾病生物学特性，并建立新的分子成像诊断和治疗程序。涵盖的一些领域包括：涉及重要生物学过程的巨分子靶标（如基因、受体、酶）的预临床和临床成像。设计、表征和研究新的分子成像探针和对比剂，以对巨分子靶标进行功能询问。成像系统（包括仪器、图像重建算法、图像分析和显示）的开发和评估。开发分子检测方法，以实现对分子成像获得的生物信息的量化。研究疾病在体动物模型，以开发新的分子诊断和治疗。将体外和体内发现通过疾病模型扩展到精心设计的临床研究调查。涉及临床调查、临床试验和医疗管理或成本效益研究的临床分子成像。