Frontiers in Molecular Biosciences

期刊简介：Much of contemporary investigation in the life sciences is devoted to the molecular-scale understanding of the relationships between genes and the environment — in particular, dynamic alterations in the levels, modifications, and interactions of cellular effectors, including proteins. Frontiers in Molecular Biosciences offers an international publication platform for basic as well as applied research; we encourage contributions spanning both established and emerging areas of biology. To this end, the journal draws from empirical disciplines such as structural biology, enzymology, biochemistry, and biophysics, capitalizing as well on the technological advancements that have enabled metabolomics and proteomics measurements in massively parallel throughput, and the development of robust and innovative computational biology strategies. We also recognize influences from medicine and technology, welcoming studies in molecular genetics, molecular diagnostics and therapeutics, and nanotechnology. Our ultimate objective is the comprehensive illustration of the molecular mechanisms regulating proteins, nucleic acids, carbohydrates, lipids, and small metabolites in organisms across all branches of life. In addition to interesting new findings, techniques, and applications, Frontiers in Molecular Biosciences will consider new testable hypotheses to inspire different perspectives and stimulate scientific dialogue. The integration of in silico, in vitro, and in vivo approaches will benefit endeavors across all domains of the life sciences.

【译文】当代生命科学研究中，很大一部分致力于基因与环境之间在分子尺度上的关系理解——特别是细胞效应物（包括蛋白质）的水平、修饰和相互作用的动态变化。分子生物科学前沿提供了一个国际出版平台，用于基础和应用研究；我们鼓励跨越生物学已建立和新兴领域的贡献。为此，该期刊从结构生物学、酶学、生物化学和生物物理学等经验学科中汲取灵感，同时充分利用技术进步，使代谢组学和蛋白质组学测量在大量并行吞吐量中成为可能，以及开发稳健和创新的计算生物学策略。我们还认识到医学和技术的影响，欢迎分子遗传学、分子诊断和治疗以及纳米技术的研究。我们的最终目标是全面展示调节生物体中蛋白质、核酸、碳水化合物、脂质和小代谢物的分子机制。