Combinatorial Chemistry & High Throughput Screening

期刊简介：Combinatorial Chemistry & High Throughput Screening (CCHTS) publishes full length original research articles and reviews/mini-reviews dealing with various topics related to chemical biology (High Throughput Screening, Combinatorial Chemistry, Chemoinformatics, Laboratory Automation and Compound management) in advancing drug discovery research. Original research articles and reviews in the following areas are of special interest to the readers of this journal:Target identification and validationAssay design, development, miniaturization and comparisonHigh throughput/high content/in silico screening and associated technologiesLabel-free detection technologies and applicationsStem cell technologiesBiomarkersADMET/PK/PD methodologies and screeningProbe discovery and development, hit to lead optimizationCombinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries)Chemical library design and chemical diversityChemo/bio-informatics, data miningCompound managementPharmacognosyNatural Products Research (Chemistry, Biology and Pharmacology of Natural Products)Natural Product Analytical StudiesBipharmaceutical studies of Natural productsDrug repurposingData management and statistical analysisLaboratory automation, robotics, microfluidics, signal detection technologiesCurrent & Future Institutional Research ProfileTechnology transfer, legal and licensing issuesPatents.

【译文】组合化学与高通量筛选（CCHTS）发表关于化学生物学（高通量筛选、组合化学、化学信息学、实验室自动化和化合物管理）相关主题的全文原创研究文章和综述/简短综述，以推进药物发现研究。本期刊读者特别感兴趣的原创研究文章和综述领域包括：靶点鉴定和验证、检测设计、开发、小型化和比较、高通量/高内涵/虚拟筛选及其相关技术、无标记检测技术和应用、干细胞技术、生物标志物、ADMET/PK/PD方法和筛选、探针发现和开发、先导化合物优化、组合化学（例如小分子、肽、核酸或噬菌体展示库）、化学库设计和化学多样性、化学/生物信息学、数据挖掘、化合物管理、药理学、天然产物研究（天然产物的化学、生物学和药理学）天然产物分析研究、天然产物双药研究、药物再利用、数据管理和统计分析、实验室自动化、机器人技术、微流控、信号检测技术、当前及未来机构研究概况、技术转让、法律和许可问题、专利。