Journal of Molecular Recognition

期刊简介：Journal of Molecular Recognition (JMR) publishes original research papers and reviews describing substantial advances in our understanding of molecular recognition phenomena in life sciences, covering all aspects from biochemistry, molecular biology, medicine, and biophysics. The research may employ experimental, theoretical and/or computational approaches.The focus of the journal is on recognition phenomena involving biomolecules and their biological / biochemical partners rather than on the recognition of metal ions or inorganic compounds. Molecular recognition involves non-covalent specific interactions between two or more biological molecules, molecular aggregates, cellular modules or organelles, as exemplified by receptor-ligand, antigen-antibody, nucleic acid-protein, sugar-lectin, to mention just a few of the possible interactions. The journal invites manuscripts that aim to achieve a complete description of molecular recognition mechanisms between well-characterized biomolecules in terms of structure, dynamics and biological activity. Such studies may help the future development of new drugs and vaccines, although the experimental testing of new drugs and vaccines falls outside the scope of the journal. Manuscripts that describe the application of standard approaches and techniques to design or model new molecular entities or to describe interactions between biomolecules, but do not provide new insights into molecular recognition processes will not be considered. Similarly, manuscripts involving biomolecules uncharacterized at the sequence level (e.g. calf thymus DNA) will not be considered.

【译文】《分子识别杂志》（JMR）发表关于生命科学中分子识别现象的理解方面的重要进展的研究论文和综述。它涵盖了从生物化学、分子生物学、医学和生物物理学等所有方面。研究可能采用实验、理论或计算方法。该杂志的重点是涉及生物分子及其生物/生化伴侣的识别现象，而不是金属离子或无机化合物的识别。分子识别涉及两个或更多生物分子、分子聚集体、细胞模块或细胞器之间的非共价特异性相互作用，例如受体-配体、抗原-抗体、核酸-蛋白质、糖-凝集素等可能的相互作用。该杂志邀请旨在从结构、动力学和生物活性等方面对已表征的生物分子之间的分子识别机制进行完整描述的手稿。这类研究可能有助于未来新药和疫苗的开发，尽管新药和疫苗的实验测试超出了该杂志的范围。描述将标准方法和技术应用于设计或建模新分子实体或描述生物分子之间相互作用的手稿，但未提供对分子识别过程的新见解，将不予考虑。同样，涉及在序列水平上未表征的生物分子（例如，牛胸腺DNA）的手稿将不予考虑。