Journal of drug targeting

期刊简介：Journal of Drug Targeting publishes papers and reviews on all aspects of drug delivery and targeting for molecular and macromolecular drugs including the design and characterization of carrier systems (whether colloidal, protein or polymeric) for both vitro and/or in vivo applications of these drugs.Papers are not restricted to drugs delivered by way of a carrier, but also include studies on molecular and macromolecular drugs that are designed to target specific cellular or extra-cellular molecules. As such the journal publishes results on the activity, delivery and targeting of therapeutic peptides/proteins and nucleic acids including genes/plasmid DNA, gene silencing nucleic acids (e.g. small interfering (si)RNA, antisense oligonucleotides, ribozymes, DNAzymes), as well as aptamers, mononucleotides and monoclonal antibodies and their conjugates. The diagnostic application of targeting technologies as well as targeted delivery of diagnostic and imaging agents also fall within the scope of the journal. In addition, papers are sought on self-regulating systems, systems responsive to their environment and to external stimuli and those that can produce programmed, pulsed and otherwise complex delivery patterns.

【译文】《药物靶向》期刊发表关于药物递送和靶向的所有方面的论文和综述，包括分子和宏分子药物载体系统（无论是胶体、蛋白质还是聚合物）的设计和表征，这些载体系统用于体外和/或体内应用。论文不仅限于通过载体递送的药物，还包括针对特定细胞或细胞外分子的分子和宏分子药物的研究。因此，该期刊发表关于治疗性肽/蛋白质和核酸（包括基因/质粒DNA、基因沉默核酸（例如小干扰（si）RNA、反义寡核苷酸、核酶、DNA酶）以及适配体、单核苷酸和单克隆抗体及其偶联物的活性、递送和靶向结果。靶向技术的诊断应用以及诊断和成像剂的靶向递送也属于该期刊的范畴。此外，还寻求关于自调节系统、对环境和外源刺激做出反应的系统以及能够产生程序化、脉冲和其他复杂递送模式的论文。