Infectious Agents and Cancer

期刊简介：Infectious Agents and Cancer is an open access, peer-reviewed online journal that encompasses all aspects of basic, clinical, epidemiological and translational research providing an insight into the association between chronic infections and cancer.The journal welcomes submissions in the pathogen-related cancer areas and other related topics, in particular:• HPV and anogenital cancers, as well as head and neck cancers;• EBV and Burkitt lymphoma;• HCV/HBV and hepatocellular carcinoma as well as lymphoproliferative diseases;• HHV8 and Kaposi sarcoma;• HTLV and leukemia;• Cancers in Low- and Middle-income countries.The link between infection and cancer has become well established over the past 50 years, and infection-associated cancer contribute up to 16% of cancers in developed countries and 33% in less developed countries.Preventive vaccines have been developed for only two cancer-causing viruses, highlighting both the opportunity to prevent infection-associated cancers by vaccination and the gaps that remain before vaccines can be developed for other cancer-causing agents. These gaps are due to incomplete understanding of the basic biology, natural history, epidemiology of many of the pathogens that cause cancer, the mechanisms they exploit to cause cancer, and how to interrupt progression to cancer in human populations. Early diagnosis or identification of lesions at high risk of progression represent the current most critical research area of the field supported by recent advances in genomics and proteomics technologies.

【译文】《感染性病原体与癌症》是一本开放获取、同行评审的在线期刊，涵盖了基础、临床、流行病学和转化研究的各个方面，揭示了慢性感染与癌症之间的关联。该期刊欢迎提交与病原体相关癌症领域以及其他相关主题的稿件，特别是：HPV与生殖器癌症以及头颈癌；EBV与伯基特淋巴瘤；HCV/HBV与肝细胞癌以及淋巴增殖性疾病；HHV8与卡波西肉瘤；HTLV与白血病；低收入和中等收入国家的癌症。在过去50年中，感染与癌症之间的联系已经得到很好的确立，感染相关癌症在发达国家占癌症总数的16%，在欠发达国家占33%。目前只有两种致癌病毒的预防疫苗已经开发出来，这既突出了通过疫苗接种预防感染相关癌症的机会，也突显了在疫苗可以针对其他致癌因素之前存在的差距。这些差距是由于对许多导致癌症的病原体的基本生物学、自然史、流行病学、它们利用来引起癌症的机制以及如何中断人类群体中癌症进展的了解不完整。早期诊断或识别高风险进展的病变是当前该领域最关键的研究领域，这一领域得到了基因组学和蛋白质组学技术的最新进展的支持。