Expert Review of Clinical Pharmacology

期刊简介：Advances in drug development technologies are yielding innovative new therapies, from potentially lifesaving medicines to lifestyle products. In recent years, however, the cost of developing new drugs has soared, and concerns over drug resistance and pharmacoeconomics have come to the fore. Adverse reactions experienced at the clinical trial level serve as a constant reminder of the importance of rigorous safety and toxicity testing. Furthermore the advent of pharmacogenomics and ‘individualized’ approaches to therapy will demand a fresh approach to drug evaluation and healthcare delivery.Clinical Pharmacology provides an essential role in integrating the expertise of all of the specialists and players who are active in meeting such challenges in modern biomedical practice.

【译文】药物开发技术的进步正在产生创新的新疗法，从可能救命的新药到生活方式产品。然而，近年来，开发新药的成本急剧上升，对药物耐药性和药物经济学的担忧也日益凸显。临床试验中出现的副作用不断提醒我们严格的安全性和毒性测试的重要性。此外，药物基因组学和针对治疗的‘个性化’方法的出现将要求对药物评估和医疗服务提供新的方法。临床药理学在现代生物医学实践中应对这些挑战发挥着至关重要的作用。