Clinical Cancer Research

期刊简介：Clinical Cancer Research publishes innovative clinical and translational cancer research studies that bridge the laboratory and the clinic. The Journal is especially interested in clinical trials evaluating new treatments, accompanied by research on pharmacology, and molecular alterations or biomarkers that predict response or resistance to treatment. The Journal also prioritizes laboratory and animal studies of new drugs and molecule-targeted agents with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of the malignant phenotype, and metastatic disease.Specific areas of interest include clinical and translational research in targeted therapies; mechanisms of drug sensitivity and resistance; pharmacogenetics and pharmacogenomics; personalized medicine; novel applications of bioinformatics and biostatistics; immunotherapy and clinical immunology; gene therapy; radiobiology and radiation oncology; large-scale molecular characterization of human tumors; diagnostic biomarkers; innovative imaging and other novel methods with potential applicability to clinical investigation; clinical genetics; and detection of minimal disease.

【译文】临床癌症研究发表创新性的临床和转化癌症研究论文，这些论文连接了实验室和临床。该期刊特别关注评估新疗法的临床试验，以及伴随的药理学研究、分子改变或预测治疗反应或耐药性的生物标志物。该期刊还优先考虑具有临床试验潜力的新药和分子靶向药物的研究，以及针对肿瘤发生、恶性表型进展和转移性疾病可靶向机制的研究。特别感兴趣的研究领域包括靶向疗法的临床和转化研究；药物敏感性和耐药性机制；药物遗传学和药物基因组学；个性化医疗；生物信息学和生物统计学的新应用；免疫治疗和临床免疫学；基因治疗；辐射生物学和放射肿瘤学；人类肿瘤的大规模分子表征；诊断生物标志物；具有潜在临床应用性的创新成像和其他新方法；临床遗传学；以及最小疾病的检测。