European Journal of Clinical Pharmacology

期刊简介：The European Journal of Clinical Pharmacology publishes original papers on all aspects of clinical pharmacology and drug therapy in humans. Manuscripts are welcomed on the following topics: therapeutic trials, pharmacokinetics/pharmacodynamics, pharmacogenetics, drug metabolism, adverse drug reactions, drug interactions, all aspects of drug development, development relating to teaching in clinical pharmacology, pharmacoepidemiology, and matters relating to the rational prescribing and safe use of drugs. Methodological contributions relevant to these topics are also welcomed.Data from animal experiments are accepted only in the context of original data in man reported in the same paper. EJCP will only consider manuscripts describing the frequency of allelic variants in different populations if this information is linked to functional data or new interesting variants. Highly relevant differences in frequency with a major impact in drug therapy for the respective population may be submitted as a letter to the editor.Straightforward phase I pharmacokinetic or pharmacodynamic studies as parts of new drug development will only be considered for publication if the paper involves-a compound that is interesting and new in some basic or fundamental way, or-methods that are original in some basic sense, or-a highly unexpected outcome, or-conclusions that are scientifically novel in some basic or fundamental sense.

【译文】欧洲临床药理学杂志发表关于人类临床药理学和药物治疗的各个方面原创论文。欢迎以下主题的稿件：治疗试验、药代动力学/药效学、药代遗传学、药物代谢、药物不良反应、药物相互作用、药物开发的各个方面、与临床药理学教学相关的发展、药源流行病学以及与药物合理处方和安全使用相关的事项。与这些主题相关的方法论贡献也欢迎。只有在同一篇论文中报告了人类原始数据的情况下，才接受动物实验数据。如果该信息与功能数据或新的有趣变异相关联，EJCP将考虑描述不同人群中等位基因变异频率的论文。如果频率差异高度相关，对相应人群的药物疗法有重大影响，则可以作为编辑信件提交。如果论文涉及在基本或根本意义上有趣且新颖的化合物、在基本意义上原创的方法、高度意外的结果或某些基本或根本意义上的科学新颖结论，则将考虑作为新药开发一部分的简单I期药代动力学或药效学研究。